Article
Genetic alterations and signaling pathways in the evolution of gliomas.
Cancer science - 1 Dec 2009
Ohgaki Hiroko, Kleihues Paul
Abstract excerpt
Gliomas are the most common primary brain tumors. They account for more than 70% of all neoplasms of the central nervous system and vary considerably in morphology, location, genetic alterations, and response to therapy. Most frequent and malignant are glioblastomas. The vast majority (>90%) deve...
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