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Article

Glioblastoma: Changing concepts in the WHO CNS5 classification.

Indian journal of pathology & microbiology - 1 May 2022

Chen Jie, Han Pengcheng, Dahiya Sonika

Abstract excerpt

Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI finding of glioblastoma is an irregularly shaped, rim-enhancing or ring-enhancing lesion with a central dark area of necrosis. This constellation of features...

Topics

Adult
Astrocytoma
Brain Neoplasms
Central Nervous System Neoplasms
Glioblastoma
Humans
Isocitrate Dehydrogenase
Mutation
Necrosis
World Health Organization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35562131
DOI: 10.4103/ijpm.ijpm_1109_21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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