Back to search

Article

A cuffed CRISPR guide RNA for microRNA activity-dependent genome editing

2026-08-10

Abstract excerpt

Cells in multicellular eukaryotic systems are diverse biological units, with characteristics and functions determined by their molecular profiles. CRISPR–Cas9 genome editing has been widely used across biology to modulate gene expression and study gene function. However, there is currently no versatile and scalable method for editing a cell’s genome in response to endogenous cellular signals. Here, we report the e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4276491e-b465-551c-a99e-a8b88785ce17
DOI
10.64898/2026.08.08.743703
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A cuffed CRISPR guide RNA for microRNA activity-dependent genome editingDOI 10.64898/2026.08.08.743703
Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering.Semantic proximity
Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAsSemantic proximity
Genetic and epigenetic control of gene expression by CRISPR–Cas systemsSemantic proximity
An integrated RNA and CRISPR/Cas toolkit for multiplexed synthetic circuits and endogenous gene regulation in human cellsSemantic proximity
Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seqSemantic proximity
Next stop for the CRISPR revolution: RNA-guided epigenetic regulators.Semantic proximity
Spligation enables programmable chimeric RNA generation in living cellsSemantic proximity
Rolling Circle Amplification With Hairpin Probes for In Situ Single-Molecule RNA Imaging at Single-Base Resolution.Semantic proximity
Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outsSemantic proximity
Systematic loss of function screens identify pathway specific functional circular RNAsSemantic proximity
Precise transcript targeting by CRISPR-Csm complexesSemantic proximity
Circular RNAs in stem cells: from basic research to clinical implications.Semantic proximity
Select a neighboring publication to make it the new centre.