Article

Development of fluorogenic RNA aptamers for cellular imaging of RNA and genomic loci

2019-01-01

Abstract excerpt

In recent years, there has been an explosion of SELEX-evolved fluorescent RNA aptamers, such as Spinach, Broccoli, Corn and Mango. Fluorogenic RNA aptamers have sparked a lot of interest and hold great potential to enable background-free visualisation of RNA molecules in cellular environments. However, their application has been limited by relatively inefficient folding in vivo and fluorescent stability. Therefore...

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Literature Corpus work: 42743d0a-f152-5144-8e8b-c3bcf803ad6c
DOI: 10.25560/75558

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