Article

Exploratory Genome Sequence Analysis of Candidate Genes Identified Three Loci Potentially Related to Mefloquine Side Effects

2026-07-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Despite effectiveness as a once-weekly antimalarial prophylaxis, mefloquine has fallen out of favor due to its neuropsychiatric side effects. While possible genetic susceptibilities have been identified in preliminary studies, pharmacogenomic testing guidance is not available for mefloquine. <h4>METHODS</h4> Volunteers with a history of mefloquine exposure were recruited to...

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Literature Corpus work: 423975cc-153d-5840-bca6-14d5ba7265a7
DOI: 10.64898/2026.07.11.26357837

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