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Article

Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D.

Psychological medicine - 1 Jun 2012

Clark S L, Adkins D E, Aberg K, Hettema J M, McClay J L, Souza R P, van den Oord E J C G

Abstract excerpt

BACKGROUND: Understanding individual differences in susceptibility to antidepressant therapy side-effects is essential to optimize the treatment of depression. METHOD: We performed genome-wide association studies (GWAS) to search for genetic variation affecting the susceptibility to side-effects. The analysis sample consisted of 1439 depression patients, successfully genotyped for 421K single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Drug-Related Side Effects and Adverse Reactions

Share to Factor Analysis, Statistical

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Source

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Identifiers

PMID: 22041458
DOI: 10.1017/S003329171100239X
PMCID: PMC3627503

Genes

CHL1
DTWD1
MAGI2
WDFY4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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