Article

AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans

2023-11-04

Abstract excerpt

Dynein complexes are large, multi-unit assemblies involved in many biological processes including male fertility via their critical roles in protein transport and axoneme motility. Previously we identified a pathogenic variant in the dynein gene AXDND1 in an infertile man. Subsequently we identified an additional four potentially compound heterozygous variants of unknown significance in AXDND1 in two additional...

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Literature Corpus work: 41ed63f4-62b5-5369-aca6-97c3786bada3
DOI: 10.1101/2023.11.02.565050

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