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AXDND1, a novel testis-enriched gene, is required for spermiogenesis and male fertility

11 Nov 2021

Abstract excerpt

Spermiogenesis is a complex process depending on the sophisticated coordination of a myriad of testis-enriched gene regulations. The regulatory pathways that coordinate this process are not well understood, and we demonstrate here that AXDND1, as a novel testis-enriched gene is essential for spermiogenesis and male fertility. AXDND1 is exclusively expressed in the round and elongating spermatids in humans and...

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PMID: 34759295
DOI: 10.1038/s41420-021-00738-z

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