Article

An Agentic Platform for Drug Repurposing Unified across Molecular, Phenotypic, and Clinical Scales

2026-04-22

Abstract excerpt

Drug repurposing offers an effective path to new therapies, yet existing computational approaches rely on a single line of evidence and are rarely validated across biological scales. We present LinkD, an integrated framework that unifies diffusion-based affinity prediction, proteome-wide selectivity scoring, phenotypic validation, and population-scale clinical evidence. LinkD-Bind predicts binding across 14,981 dr...

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Identifiers and source

Literature Corpus work: 418dac8d-9392-5467-beab-e5431dec7c17
DOI: 10.64898/2026.04.19.719462

Open publication

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