Article

Computational repurposing of oncology drugs through off-target drug binding interactions from pharmacological databases

2023-07-01

Abstract excerpt

<h4>PURPOSE</h4> Systematic repurposing of approved medicine for another indication represents an attractive strategy to accelerating drug development in oncology. Herein we present a strategy of combining biomarker testing with drug repurposing to identify new treatments for patients with advanced cancer. <h4>METHODS</h4> Tumours were sequenced with Illumina TruSight Oncology 500 (TSO-500) platform or the Found...

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Literature Corpus work: 680a273a-52af-5457-bc64-38c8e4a2f027
DOI: 10.1101/2023.07.01.547311

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