Article

An Integrated Knowledge Graph and Network Medicine Pipeline for Drug Repurposing: Benchmarking Across Human Diseases and Application to Amyotrophic Lateral Sclerosis

2026-07-08

Abstract excerpt

Drug repurposing offers a practical strategy to identify new therapeutic uses for approved drugs, potentially reducing the time and cost associated with conventional drug development. We present a novel three-stage drug repurposing pipeline that integrates knowledge graph-based gene prediction, network-based drug-disease association analysis, and systematic classification of candidate drugs by therapeutic class. T...

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Literature Corpus work: 48fbe05b-fce8-585f-8d7d-5bca4d09253b
DOI: 10.64898/2026.07.03.736387

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