Article

Benchmarking transcriptional deconvolution methods for estimating tissue- and cell type-specific extracellular vesicle abundances

2024-03-01

Abstract excerpt

Extracellular vesicles (EVs) contain cell-derived lipids, proteins, and RNAs; however, the challenge to determine the tissue- and cell type-specific EV abundances in body fluids remains a significant hurdle for our understanding of EV biology. While tissue- and cell type-specific EV abundances can be estimated by matching the EV’s transcriptome to a tissue’s/cell type’s expression signature using deconvolutional m...

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Literature Corpus work: 41498ac8-94eb-5881-886f-ffdd6023d70b
DOI: 10.1101/2024.02.27.582268

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