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Article

Systematic evaluation of transcriptomics-based deconvolution methods and references using thousands of clinical samples

2021-03-10

Abstract excerpt

Estimating cell type composition of blood and tissue samples is a biological challenge relevant in both laboratory studies and clinical care. In recent years, a number of computational tools have been developed to estimate cell type abundance using gene expression data. While these tools use a variety of approaches, they all leverage expression profiles from purified cell types to evaluate the cell type compositio...

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Literature Corpus work
8c0daab3-cf30-5186-a31a-7583ac027e95
DOI
10.1101/2021.03.09.434660
Open publication

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Systematic evaluation of transcriptomics-based deconvolution methods and references using thousands of clinical samplesDOI 10.1101/2021.03.09.434660
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