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Fibroblast-derived Osteoglycin Promotes Epithelial Cell Repair

2024-11-15

Abstract excerpt

<h4>ABSTRACT</h4> There is an urgent need for innovative pharmacological treatments targeting defective epithelial repair in chronic diseases, such as chronic obstructive pulmonary disease. The mesenchymal niche is a critical regulator in epithelial stem cell activation during repair. We hypothesized that secreted factors in this interaction are potent drug targets. Utilizing a cutting-edge proteomics-guided drug...

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Identifiers and source

Literature Corpus work
410789b2-6a72-5bd2-9083-5dee53d577c3
DOI
10.1101/2024.11.14.623606
Open publication

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Fibroblast-derived Osteoglycin Promotes Epithelial Cell RepairDOI 10.1101/2024.11.14.623606
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