Article

PTX3 Governs Fibroblast-Epithelial Dynamics in Lung Injury and Repair

2024-12-04

Abstract excerpt

Dysfunctional interactions between fibroblasts and epithelial cells contribute to the progression of chronic lung diseases, including idiopathic pulmonary fibrosis (IPF). In this study, we utilized a coculture model of human small airway epithelial cells and fibroblasts to investigate intercellular communication during disease progression. Our transcriptomic and proteomic profiling reveal that fibroblasts repair e...

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Literature Corpus work: 6f8c9e36-f653-5c0b-9496-b85e2f01bbe1
DOI: 10.1101/2024.12.03.626584

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