Article

SARM1 deficiency preferentially protects against autonomic over somatic neuropathy in type 2 diabetic db/db mice by preserving mitochondrial integrity

2026-08-13

Abstract excerpt

<title>Abstract</title> Diabetic peripheral neuropathy (DPN) is a common and disabling complication of diabetes encompassing both sensory and autonomic subtypes. Using a genetic type 2 diabetic (db/db) mouse model, we investigated the role of SARM1 (sterile alpha and TIR motif-containing protein 1) in the development and progression of DPN, with a specific focus on potential subtype-specific effects and underl...

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Literature Corpus work: 40c9a2ed-6d35-5243-9ee7-2d56ce280a87
DOI: 10.21203/rs.3.rs-10308239/v1

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