Article
An explicative review on Diabetic Cardiac Autonomic Neuropathy: From pathophysiology to the era of gene therapy.
Vascular pharmacology - 1 Sept 2026
Chakravarti Rudra, Bankar Payal Ramesh, Chigilipalli Jhanshi, Roy Dipanjan, Bhattacharya Bireswar, Pradhan Aditya Kumar, Singh Rashmi, Arya Mansi, Kundu Anirban, Ghosh Dipanjan
Abstract excerpt
Diabetic Cardiac Autonomic Neuropathy (DCAN) is a prevalent and severe yet underdiagnosed complication of diabetes characterized by progressive injury to autonomic nerve fibers that regulate cardiovascular functions. This multifactorial disorder contributes significantly to morbidity and mortality due to arrhythmias, silent myocardial ischemia, and sudden cardiac death. DCAN onset is often insidious, with early...
Read the complete abstract on PubMedTopics
- Humans
- Diabetic Neuropathies
- Animals
- Genetic Therapy
- Autonomic Nervous System
- Heart