Article

DYRK1A haploinsufficiency affects the development of astroglia and oligodendroglia, and axonal conductivity in the brain

2022-08-08

Abstract excerpt

<h4>Background: </h4> The correct development and activity of neurons and glial cells, and the interplay between them, is necessary to establish proper brain connectivity. DYRK1A encodes a protein kinase that influences neurogenesis and the morphological differentiation of neurons. Indeed, it is a gene associated with a risk of autism spectrum disorders. DYRK1A loss-of-function mutations cause a rare disorder in h...

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Literature Corpus work: 40aa1e8c-3812-5ca8-839f-d9bcbdbd6784
DOI: 10.21203/rs.3.rs-1925334/v1

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