Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion Behaviors

13 Mar 2024

Abstract excerpt

The role of RNA Binding Motif Protein 8a (RBM8A), an exon junction complex (EJC) component, in neurodevelopmental disorders has been increasingly studied for its crucial role in regulating multiple levels of gene expression. It regulates mRNA splicing, translation, and mRNA degradation and influences embryonic development. RBM8A protein is expressed in both neurons and astrocytes, but little is known about...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenetic and Muscular Disorders Research
Share to RNA regulation and disease
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38534343
DOI: 10.3390/cells13060498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion BehaviorsPMID 38534343Read ↗

TAR syndrome causal gene RBM8A is critical for embryonic bone development and proper Hedgehog signalingSemantic proximity Read ↗

Molecular basis of astrocyte diversity and morphology across the CNS in health and diseaseSemantic proximity Read ↗

Brain Region-Specific Gene Signatures Revealed by Distinct Astrocyte Subpopulations Unveil Links to Glioma and Neurodegenerative Diseases.Semantic proximity Read ↗

MeCP2 Deficiency Leads to Loss of Glial Kir4.1Semantic proximity Read ↗

TAR syndrome causal gene <i>RBM8A</i> is critical for embryonic bone development and proper Hedgehog signalingSemantic proximity Read ↗

Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic SignaturesSemantic proximity Read ↗

DYRK1A haploinsufficiency affects the development of astroglia and oligodendroglia, and axonal conductivity in the brainSemantic proximity Read ↗

Ezrin deficiency triggers glial fibrillary acidic protein upregulation and a distinct reactive astrocyte phenotype.Semantic proximity Read ↗

Astrocytic Chromatin Remodeler ATRX Gates Hippocampal Memory Consolidation through Metabolic and Synaptic RegulationSemantic proximity Read ↗

WWOX P47T loss-of-function mutation induces epilepsy, progressive neuroinflammation, and cerebellar degeneration in mice phenocopying human SCAR12Semantic proximity Read ↗

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.Semantic proximity Read ↗

Suppression of astrocyte BMP signaling improves fragile X syndrome molecular signatures and functional deficitsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.