Article

Genetic factors associated with anti-factor H autoantibodies in atypical hemolytic uremic syndrome (aHUS)

2018-01-01

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy characterized by renal failure and determined by genetic and acquired defects of alternative pathway (AP) of the complement system. Autoantibodies against factor H (anti-FHs), a regulator of the AP, were reported in 10% of patients, and are associated with the deficiency of factor H related 1 (FHR1), a FH homologous protein. The...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 40926afb-2930-51e7-8df2-3487f7663a38
DOI: 10.21954/ou.ro.0000da2d

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic factors associated with anti-factor H autoantibodies in atypical hemolytic uremic syndrome (aHUS)DOI 10.21954/ou.ro.0000da2dRead

IgM Autoantibodies to Complement Factor H in Atypical Hemolytic Uremic SyndromeSemantic proximity Read

Rare Functional Variants in Complement Genes and Anti-FH Autoantibodies-Associated aHUSSemantic proximity Read

Advances in understanding the aetiology of atypical Haemolytic Uraemic Syndrome.Semantic proximity Read

[Atypical hemolytic uremic syndrome].Semantic proximity Read

Atypical hemolytic uremic syndrome, genetic basis, and clinical manifestations.Semantic proximity Read

Overall Neutralization of Complement Factor H by Autoantibodies in the Acute Phase of the Autoimmune Form of Atypical Hemolytic Uremic SyndromeSemantic proximity Read

Atypical Hemolytic Uremic Syndrome: A Meta-Analysis of Case Reports Confirms the Prevalence of Genetic Mutations and the Shift of Treatment Regimens.Semantic proximity Read

[Human genetics in atypical hemolytic uremic syndrome-its role in diagnosis and treatment].Semantic proximity Read

[Atypical hemolytic-uremic syndrome related to abnormalities within the complement system].Semantic proximity Read

The genetics of atypical hemolytic uremic syndromeSemantic proximity Read

Anti-factor B antibodies in atypical hemolytic uremic syndromeSemantic proximity Read

A review of genetic and epigenetic biomarkers involved in the occurrence of atypical hemolytic uremic syndrome and its therapeutic strategies.Semantic proximity Read