Article
Advances in understanding the aetiology of atypical Haemolytic Uraemic Syndrome.
British journal of haematology - 1 Sept 2010
Sánchez-Corral Pilar, Melgosa Marta
Abstract excerpt
Atypical Haemolytic Uraemic Syndrome (aHUS) is a thrombotic microangiopathy that often provokes irreversible renal damage and post-transplantation recurrence. Studies performed during the last decade have shown that 50-60% of aHUS patients present genetic or acquired defects in the complement system that enhance the initial endothelial damage and favour disease development. This review analyses the complement...
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