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Wnt signaling modulates the response to DNA damage in the <i>Drosophila</i> wing imaginal disc by regulating the EGFR pathway

2024-02-13

Abstract excerpt

Despite the deep conservation of the DNA damage response pathway (DDR), cells in different contexts vary widely in their susceptibility to DNA damage and their propensity to undergo apoptosis as a result of genomic lesions. One of the cell signaling pathways implicated in modulating the DDR is the highly conserved Wnt pathway, which is known to promote resistance to DNA damage caused by ionizing radiation in a var...

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Identifiers and source

Literature Corpus work
4080779e-0a91-59f3-9346-c989796903f6
DOI
10.1101/2024.02.13.580041
Open publication

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