Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in <i>Drosophila</i>

Abstract excerpt

In Drosophila, stresses such as x-irradiation or severe heat shock can cause most epidermal cells to die by apoptosis. Yet, the remaining cells recover from such assaults and form normal adult structures, indicating that they undergo extra growth to replace the lost cells. Recent studies of cells in which the cell death pathway is blocked by expression of the caspase inhibitor P35 have raised the possibility that...

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