Article

Integrative bulk and single-cell transcriptomic analyses identify progression-associated programs and a prognostic index in osteosarcoma

2026-05-22

Abstract excerpt

<title>Abstract</title> <p>Background Osteosarcoma (OS) is a highly heterogeneous malignancy with poor outcomes in metastatic disease. Progression-related molecular programs and their cellular contexts remain incompletely characterized, and clinically useful prognostic stratification remains challenging. Methods We integrated bulk transcriptomic and single-cell RNA sequencing (scRNA-seq) data to identify progre...

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Literature Corpus work: 3131c219-6b0c-527d-918c-bd7f51e88b7c
DOI: 10.21203/rs.3.rs-9497077/v1

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