Article

New insights on human essential genes based on integrated analysis

2018-02-05

Abstract excerpt

Essential genes are those whose functions govern critical processes that sustain life in the organism. Recent gene-editing technologies have provided new opportunities to characterize essential genes. Here, we present an integrated analysis for comprehensively and systematically elucidating the genetic and regulatory characteristics of human essential genes. First, essential genes act as “hubs” in protein-protein...

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Literature Corpus work: c83462fc-387f-5237-ad68-a4c137410330
DOI: 10.1101/260224

Open publication

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