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Article

CEN-tools: an integrative platform to identify the contexts of essential genes.

Molecular systems biology - 1 Oct 2020

Sharma Sumana, Dincer Cansu, Weidemüller Paula, Wright Gavin J, Petsalaki Evangelia

Abstract excerpt

An emerging theme from large-scale genetic screens that identify genes essential for cell fitness is that essentiality of a given gene is highly context-specific. Identification of such contexts could be the key to defining gene function and also to develop novel therapeutic interventions. Here, we present Context-specific Essentiality Network-tools (CEN-tools), a website and python package, in which users can...

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Identifiers

PMID: 33073517
DOI: 10.15252/msb.20209698
PMCID: PMC7569414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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