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Article

Overview of Research on Germline Genetic Variation in Immune Genes and Cancer Outcomes.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2022

Chao Brittany N, Carrick Danielle M, Filipski Kelly K, Nelson Stefanie A

Abstract excerpt

Since the late 19th century, the immune system has been known to play a role in cancer risk, initiation, and progression. Genome-wide association studies (GWAS) have identified hundreds of genetic risk loci for autoimmune and inflammatory diseases, yet the connection between human genetic variation and immune-mediated response to cancer treatments remains less well-explored. Understanding inherited genetic...

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Identifiers

PMID: 35027433
DOI: 10.1158/1055-9965.EPI-21-0583
PMCID: PMC8901557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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