Article

Plasma Sphingomyelin Disturbances: Unveiling Its Dual Role as a Crucial Imunopathological Factor and a Severity Prognostic Biomarker in COVID-19

2023-06-12

Abstract excerpt

SARS-CoV-2 infection triggers distinct patterns of disease development, characterized by significant alterations in host regulatory responses. Severe cases exhibit profound lung inflammation and systemic repercussions. Remarkably, critically ill patients display a "lipid storm", influencing the inflammatory process and tissue damage. Sphingolipids (SL) play pivotal roles in various cellular and tissue pr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a1cbdad9-3d5d-5070-a60a-1dc559df2b81
DOI: 10.20944/preprints202306.0752.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Plasma Sphingomyelin Disturbances: Unveiling Its Dual Role as a Crucial Imunopathological Factor and a Severity Prognostic Biomarker in COVID-19DOI 10.20944/preprints202306.0752.v1Read

Polyunsaturated fatty acid-derived lipid mediator networks characterize COVID-19 severity and risk for critical illnessSemantic proximity Read

Dynamic lipidome alterations associated with human health, disease and ageingSemantic proximity Read

Dysregulated Bioactive Lipid Profiles Characterize Inflammation in Philadelphia-Negative Myeloproliferative NeoplasmsSemantic proximity Read

Dihydroceramides: their emerging physiological roles and functions in cancer and metabolic diseasesSemantic proximity Read

Deep Phenotyping of the Lipidomic Response in COVID and non-COVID SepsisSemantic proximity Read

Diagnostic, Prognostic and Mechanistic Biomarkers of COVID-19 Identified by Mass Spectrometric MetabolomicsSemantic proximity Read

Valuable Contributions and Lessons Learned from Proteomics and Metabolomics Studies of COVID-19Semantic proximity Read

Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infectionSemantic proximity Read

Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological Metabolic Phenotypes.Semantic proximity Read

Molecular Phenomic Approaches to Deconvolving the Systemic Effects of SARS-CoV-2 Infection and Post-acute COVID-19 SyndromeSemantic proximity Read

The role of cholesterol metabolism in predicting clinical outcome of patients with severe COVID-19Semantic proximity Read

Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics AnalysisSemantic proximity Read