Article

Xdrop: targeted sequencing of long DNA molecules from low input samples using droplet sorting

2018-09-06

Abstract excerpt

Long-read sequencing can resolve regions of the genome that are inaccessible to short reads, and therefore such technologies are ideal for genome-gap closure, solving structural rearrangements and sequencing through repetitive elements. Here we introduce the Xdrop technology: a novel microfluidic-based system that allows for targeted enrichment of long DNA molecules starting from only a few nanograms of genomic DN...

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Literature Corpus work: 3fccc516-560d-5158-b233-c71567aede82
DOI: 10.1101/409086

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