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Article

Microfluidic droplet enrichment for targeted sequencing.

Nucleic acids research - 27 Jul 2015

Eastburn Dennis J, Huang Yong, Pellegrino Maurizio, Sciambi Adam, Ptáček Louis J, Abate Adam R

Abstract excerpt

Targeted sequence enrichment enables better identification of genetic variation by providing increased sequencing coverage for genomic regions of interest. Here, we report the development of a new target enrichment technology that is highly differentiated from other approaches currently in use. Our method, MESA (Microfluidic droplet Enrichment for Sequence Analysis), isolates genomic DNA fragments in microfluidic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25873629
DOI: 10.1093/nar/gkv297
PMCID: PMC4513844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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