Article

Ultra-fast sample-to-sequencing workflow for clinical diagnostics using micropillars

2026-01-30

Abstract excerpt

We present a streamlined, solid-phase workflow for Oxford Nanopore sequencing that integrates DNA extraction, purification, and library preparation within a single microfluidic cartridge. By eliminating tube transfers and performing all enzymatic steps directly on captured DNA, the method minimizes sample loss, reduces hands-on time, and simplifies library generation for long-read sequencing. Starting from volumes...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 75e87b9a-aa6b-5e0f-a534-2afdafd7cedc
DOI: 10.64898/2026.01.29.26345156

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultra-fast sample-to-sequencing workflow for clinical diagnostics using micropillarsDOI 10.64898/2026.01.29.26345156Read

High-throughput automated microfluidic sample preparation for accurate microbial genomics.Semantic proximity Read

An Introduction to Nanopore Sequencing: Past, Present, and Future ConsiderationsSemantic proximity Read

AM‑DMF-Lib-prep: A clinical ready lib-prep-on-a-chip platform with active-matrix digital microfluidicsSemantic proximity Read

High-throughput single cell -omics using semi-permeable capsulesSemantic proximity Read

An active-matrix digital microfluidic platform for simultaneous short- and long-read viral genomic surveillanceSemantic proximity Read

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis productSemantic proximity Read

Device for whole genome sequencing single circulating tumor cells from whole bloodSemantic proximity Read

"Sample-to-Answer" Detection of Rare ctDNA Mutation from 2 mL Plasma with a Fully Integrated DNA Extraction and Digital Droplet PCR Microdevice for Liquid Biopsy.Semantic proximity Read

CAS12A-TARGETED MULTIPLEXED NANOPORE SEQUENCINGSemantic proximity Read

BLADE-R: streamlined RNA extraction for molecular diagnostics and high-throughput applicationsSemantic proximity Read

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis productSemantic proximity Read

Exploring the potential of Oxford Nanopore Technologies sequencing for Mycobacterium tuberculosis sequencing: An assessment of R10 flowcells and V14 chemistrySemantic proximity Read