Article

Adaptive changes in the fungal cell wall mediate copper homeostasis

2021-12-14

Abstract excerpt

Copper homeostasis mechanisms are essential for microbial adaption to changing copper levels within the host during infection. In the opportunistic fungal pathogen Cryptococcus neoformans ( Cn ), the Cn Cbi1/Bim1 protein is a newly identified copper binding and release protein that is highly induced during copper limitation. Recent studies demonstrated that Cbi1 functions in copper uptake through the Ctr1 coppe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3fb34839-4c3b-5091-a73c-6782c311c6c8
DOI: 10.1101/2021.12.14.472543

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adaptive changes in the fungal cell wall mediate copper homeostasisDOI 10.1101/2021.12.14.472543Read

A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read

The copper regulon of the human fungal pathogen<i>Cryptococcus neoformans</i>H99Semantic proximity Read

A cysteine-rich domain of the <i>Cryptococcus neoformans</i> Cuf1 transcription factor is required for high copper stress sensing and fungal virulenceSemantic proximity Read

Transcriptome analysis uncovers a link between copper metabolism, and both fungal fitness and antifungal sensitivity in the opportunistic yeast <i>Candida albicans</i>Semantic proximity Read

Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicansSemantic proximity Read

A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformansSemantic proximity Read

Role of a CUF1/CTR4 copper regulatory axis in the virulence of Cryptococcus neoformansSemantic proximity Read

Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans.Semantic proximity Read

Genome‐wide analysis of the regulation of Cu metabolism in Cryptococcus neoformansSemantic proximity Read

A copper hyperaccumulation phenotype correlates with pathogenesis in Cryptococcus neoformans.Semantic proximity Read

Chitosan biosynthesis and virulence in the human fungal pathogen <i>Cryptococcus gattii</i>Semantic proximity Read

Novel cell wall-associated genes that enable <i>Cryptococcus neoformans</i> to evade dectin-1-mediated innate immune recognitionSemantic proximity Read