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Novel cell wall-associated genes that enable <i>Cryptococcus neoformans</i> to evade dectin-1-mediated innate immune recognition

2026-07-28

Abstract excerpt

The fungal pathogen Cryptococcus neoformans contains about 200 µg of β-1,3-glucan (1,3BG) per 1 mg of dry cell weight when grown under standard culture conditions (YPD medium at 30 °C under aerobic conditions). However, 1,3BG exposure is tightly suppressed, even in capsule-deficient strains, allowing the fungus to evade recognition by the immune receptor dectin-1 and anti-1,3BG antibodies. Although other pathogen...

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Identifiers and source

Literature Corpus work
49953160-f0b3-578a-8829-8ca04ab2fcb5
DOI
10.64898/2026.07.27.740439
Open publication

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Novel cell wall-associated genes that enable <i>Cryptococcus neoformans</i> to evade dectin-1-mediated innate immune recognitionDOI 10.64898/2026.07.27.740439
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