Article
Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans.
Molecular microbiology - 1 Sept 2005
Walton Felicia J, Idnurm Alexander, Heitman Joseph
Abstract excerpt
The ability to produce melanin is a key virulence factor in many fungal pathogens including the human basidiomycete pathogen Cryptococcus neoformans, a major cause of life-threatening infections among immunocompromised persons. Despite the significance of melanin biosynthesis in virulence of C. neoformans, the cellular and molecular processes involved in this pathway have not yet been fully elucidated. Here, we...
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