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<i>Isoquercetin treatment of mouse sickled red blood cells shows a</i> discernible deformability and sickling phenotype

2026-04-28

Abstract excerpt

<h4>Introduction</h4> Sickle cell disease is an inherited hemoglobinopathy with defective red cell deformability. The defective deformability promotes microvascular occlusion and subsequent vaso-occlusion in sickle cell disease patients. Previous studies have demonstrated that thiol isomerases, an endoplasmic reticulum-resident oxidoreductase that is released from vascular cells into the bloodstream, are present...

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Literature Corpus work
3f957e55-64be-5964-87e3-f4f43715cf59
DOI
10.64898/2026.04.24.720679
Open publication

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