Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes.

Nature communications - 8 Nov 2016

Cyrklaff Marek, Srismith Sirikamol, Nyboer Britta, Burda Kvetoslava, Hoffmann Angelika, Lasitschka Felix, Adjalley Sophie, Bisseye Cyrille, Simpore Jacques, Mueller Ann-Kristin, Sanchez Cecilia P, Frischknecht Friedrich, Lanzer Michael

Abstract excerpt

Plasmodium falciparum infections can cause severe malaria, but not every infected person develops life-threatening complications. In particular, carriers of the structural haemoglobinopathies S and C and infants are protected from severe disease. Protection is associated with impaired parasite-induced host actin reorganization, required for vesicular trafficking of parasite-encoded adhesins, and reduced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Erythrocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobins

Share to Malaria, Falciparum

Share to Plasmodium berghei

Share to Plasmodium falciparum

Share to Vitamin K 3

Source

Open in PubMed Open full text

Identifiers

PMID: 27824335
DOI: 10.1038/ncomms13401
PMCID: PMC5105170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes.PMID 27824335Read ↗

Host actin remodeling and protection from malaria by hemoglobinopathiesSemantic proximity Read ↗

The triumph of good over evil: protection by the sickle gene against malaria.Semantic proximity Read ↗

Hemoglobinopathies: Slicing the Gordian Knot of Plasmodium falciparum Malaria PathogenesisSemantic proximity Read ↗

Malaria and the red cell.Semantic proximity Read ↗

The role of the red blood cell in host defence against falciparum malaria: an expanding repertoire of evolutionary alterationsSemantic proximity Read ↗

Differential carbonylation of cytoskeletal proteins in blood group O erythrocytes: potential role in protection against severe malaria.Semantic proximity Read ↗

Peroxide antimalarial drugs target redox homeostasis in <i>Plasmodium falciparum</i> infected red blood cellsSemantic proximity Read ↗

Haemoglobinopathies and resistance to malaria.Semantic proximity Read ↗

Erythrocyte remodeling by malaria parasitesSemantic proximity Read ↗

Impact of sickle cell trait hemoglobin on the intraerythrocytic transcriptional program of <i>Plasmodium falciparum</i>Semantic proximity Read ↗

A druggable oxidative folding pathway in the endoplasmic reticulum of human malaria parasitesSemantic proximity Read ↗

Manipulating Eryptosis of Human Red Blood Cells: A Novel Antimalarial Strategy?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.