Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse

27 Jun 2020

Abstract excerpt

Significance: Red blood cell (RBC)-mediated vasodilation plays an important role in oxygen delivery. This occurs through hemoglobin actions, at least in significant part, to convert heme-bound nitric oxide (NO) (in tense [T]/deoxygenated-state hemoglobin) into vasodilator S-nitrosothiol (SNO) (in relaxed [R]/oxygenated-state hemoglobin), convey SNO through the bloodstream, and release it into tissues to increase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocyte Function and Pathophysiology
Share to Hemoglobin structure and function
Share to Neuroscience of respiration and sleep

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32597195
DOI: 10.1089/ars.2020.8153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In MousePMID 32597195Read ↗

Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation.Semantic proximity Read ↗

Quercetin Completely Ameliorates Hypoxia-Reoxygenation-Induced Pathophysiology Severity in NY1DD Transgenic Sickle Mice: Intrinsic Mild Steady State Pathophysiology of the Disease in NY1DD Is Also Reversed.Semantic proximity Read ↗

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.Semantic proximity Read ↗

Impaired vasodilation by red blood cells in sickle cell disease.Semantic proximity Read ↗

Therapeutic potential of oxygen through M101 transportation in reducing vaso-occlusion and hemolysis in a mouse model of sickle cell diseaseSemantic proximity Read ↗

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.Semantic proximity Read ↗

Nitric oxide in cellular adaptation and diseaseSemantic proximity Read ↗

The Gasotransmitter Trio (NO, CO, H₂S) in Cardiovascular Health and Disease: From Molecular Crosstalk to Precision Gas MedicineSemantic proximity Read ↗

Deep Red Blood Cell Proteome Defines the Band 3 N-Terminus Interactome as a Regulator of Hypoxic Adaptation via BLVRB-Dependent <i>S</i> -Nitroso TransferSemantic proximity Read ↗

A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyureaSemantic proximity Read ↗

Sickle cell anemia and vascular dysfunction: the nitric oxide connection.Semantic proximity Read ↗

Cross-talk between NO and oxyradicals, a supersystem that regulates energy metabolism and survival of animals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.