Article

Population scale whole genome sequencing provides novel insights into cardiometabolic health

2024-05-27

Abstract excerpt

In addition to its coverage of the non-coding genome, whole genome sequencing (WGS) may better capture the coding genome than exome sequencing. We sought to exploit this and identify novel rare, protein-coding variants associated with metabolic health in newly released WGS data (N=708,956) from the UK Biobank and All of Us studies. Identified genes highlight novel biological mechanisms, including protein truncatin...

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Literature Corpus work: 3f95321c-0409-55ce-9f76-173dfc5cfd74
DOI: 10.1101/2024.05.27.24307970

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