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Article

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Journal of human genetics - 1 Aug 2023

Wang Xin, Ryu Justine, Kim Jihoon, Ramirez Andrea, Mayo Kelsey R, Condon Henry, Vaitinadin Nataraja Sarma, Ohno-Machado Lucila, Talavera Greg A, Ellinor Patrick T, Lubitz Steven A, Choi Seung Hoan

Abstract excerpt

All of Us is a biorepository aiming to advance biomedical research by providing various types of data in diverse human populations. Here we present a demonstration project validating the program's genomic data in 98,622 participants. We sought to replicate known genetic associations for three diseases (atrial fibrillation [AF], coronary artery disease, type 2 diabetes [T2D]) and two quantitative traits (height...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37072623
DOI: 10.1038/s10038-023-01147-z
PMCID: PMC10524735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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