Article

Population-scale Long-read Sequencing in the All of Us Research Program

2025-10-05

Abstract excerpt

The All of Us Research Program (AoU) is a national biobank seeking to enroll one million individuals in the United States to link genomic and biomedical data, including short- and long-read whole-genome sequencing (srWGS/LRS), with rich electronic health record (EHR) information. Here, we present the first large-scale analyses of long-read sequencing (LRS) in AoU and offer a new framework for deriving genomic insi...

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Literature Corpus work: f8118dcc-8d5a-553d-91a7-b940af5de581
DOI: 10.1101/2025.10.02.25336942

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