Article

Reduction of <i>Grin2a</i> in adolescent rat dopamine neurons confers a phenotype relevant to psychosis

2024-10-28

Abstract excerpt

<h4>SUMMARY</h4> Psychosis is a hallmark of schizophrenia. It involves a collection of symptoms that are typically associated with disrupted dopamine signaling and emerges during adolescence or early adulthood. Most schizophrenia-associated genes, however, involve glutamatergic or other ubiquitous targets that do not explain the latent expression of psychosis or dopaminergic abnormalities. Here, we describe an et...

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Literature Corpus work: 3f784ee7-8f14-5977-aa83-df14600deb0b
DOI: 10.1101/2024.10.28.620713

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