Article
GRIN2A (NR2A): a gene contributing to glutamatergic involvement in schizophrenia.
Molecular psychiatry - 1 Sept 2023
Harrison Paul J, Bannerman David M
Abstract excerpt
Involvement of the glutamate system, particularly N-methyl-D-aspartate (NMDA) receptor hypofunction, has long been postulated to be part of the pathophysiology of schizophrenia. An important development is provided by recent data that strongly implicate GRIN2A, the gene encoding the NR2A (GluN2A) NMDA receptor subunit, in the aetiology of the disorder. Rare variants and common variants are both robustly...
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