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Article

Differential depletion of GluN2A induces heterogeneous schizophrenia-related phenotypes in mice

11 Mar 2024

Abstract excerpt

BACKGROUND: Schizophrenia, a debilitating psychiatric disorder, displays considerable interindividual variation in clinical presentations. The ongoing debate revolves around whether this heterogeneity signifies a continuum of severity linked to a singular causative factor or a collection of distinct subtypes with unique origins. Within the realm of schizophrenia, the functional impairment of GluN2A, a subtype of...

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PMID: 38471394
DOI: 10.1016/j.ebiom.2024.105045

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