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A <i>Drosophila</i> screen of schizophrenia-related genes highlights the requirement of neural and glial matrix metalloproteinases for neuronal remodeling

2024-10-02

Abstract excerpt

Schizophrenia (SCZ) is a multifactorial neuropsychiatric disorder of complex and mostly unknown etiology, affected by genetic, developmental and environmental factors. Neuroanatomical abnormalities, such as loss of grey matter, are apparent prior to the onset of symptoms, suggesting neurodevelopmental origin. Indeed, it has been hypothesized, and recently experimentally supported, that SCZ is associated with dysre...

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Literature Corpus work
3f1e0d62-2d6e-52e1-814a-8e92892f24f6
DOI
10.1101/2024.10.01.616025
Open publication

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A <i>Drosophila</i> screen of schizophrenia-related genes highlights the requirement of neural and glial matrix metalloproteinases for neuronal remodelingDOI 10.1101/2024.10.01.616025
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