Article

Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors

2024-08-18

Abstract excerpt

De novo mutations in transcriptional regulators are emerging as key risk factors contributing to the etiology of neurodevelopmental disorders. Human genetic studies have recently identified ZMIZ1 and its de novo mutations as causal of a neurodevelopmental syndrome strongly associated with intellectual disability, autism, ADHD, microcephaly, and other developmental anomalies. However, the role of ZMIZ in brain deve...

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Literature Corpus work: 4d61c077-01b2-51da-9580-7114b465a2d4
DOI: 10.1101/2024.08.18.608498

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