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Article

Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous system.

Development (Cambridge, England) - 1 Jul 2002

Egger Boris, Leemans Ronny, Loop Thomas, Kammermeier Lars, Fan Yun, Radimerski Tanja, Strahm Martin C, Certa Ulrich, Reichert Heinrich

Abstract excerpt

In Drosophila, the glial cells missing (gcm) gene encodes a transcription factor that controls the determination of glial versus neuronal fate. In gcm mutants, presumptive glial cells are transformed into neurons and, conversely, when gcm is ectopically misexpressed, presumptive neurons become glia. Although gcm is thought to initiate glial cell development through its action on downstream genes that execute the...

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PMID: 12091301
DOI: 10.1242/dev.129.14.3295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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