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Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s disease

20 Sept 2020

Abstract excerpt

BACKGROUND: There is an urgent need to understand the pathways and processes underlying Alzheimer's disease (AD) for early diagnosis and development of effective treatments. This study was aimed to investigate Alzheimer's dementia using an unsupervised lipid, protein and gene multi-omics integrative approach. METHODS: A lipidomics dataset comprising 185 AD patients, 40 mild cognitive impairment (MCI) individuals...

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PMID: 32951606
DOI: 10.1186/s40035-020-00215-0

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