Dating genomic variants and shared ancestry in population-scale sequencing data

Abstract excerpt

The origin and fate of new mutations within species is the fundamental process underlying evolution. However, while much attention has been focused on characterizing the presence, frequency, and phenotypic impact of genetic variation, the evolutionary histories of most variants are largely unexplored. We have developed a non-parametric approach for estimating the date of origin of genetic variants in large-scale s...

Topics

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• Age Factors
• Computer Simulation
• Datasets as Topic
• Genetic Speciation
• Genome, Human
• High-Throughput Nucleotide Sequencing
• Racial Groups
• Statistics as Topic

Identifiers and source

Literature Corpus work

3f137543-b20a-5c02-a887-675faab7f7e7

DOI

10.1101/416610