Article
A haplotype sharing method for determining the relative age of SNP alleles.
Human heredity - 1 Jan 2010
de Vries André R, te Meerman Gerard J
Abstract excerpt
There are two aspects regarding the age of alleles that are relevant as indicators of the timing of mutational events. The first is to know which alleles are species-specific; the second is about the time of origin of species-specific alleles. Both aspects can be analyzed using haplotype-sharing methods, by using the length of shared haplotypes as a measure of the speed of coalescence to common ancestors. The...
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