Article
Dating genomic variants and shared ancestry in population-scale sequencing data.
PLoS biology - 1 Jan 2020
Albers Patrick K, McVean Gil
Abstract excerpt
The origin and fate of new mutations within species is the fundamental process underlying evolution. However, while much attention has been focused on characterizing the presence, frequency, and phenotypic impact of genetic variation, the evolutionary histories of most variants are largely unexplored. We have developed a nonparametric approach for estimating the date of origin of genetic variants in large-scale...
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